APEX1 Antibody
Product Sizes
100ul
£630.00
OAGA03611-100UL
About this Product
- SKU:
- OAGA03611
- Additional Names:
- APE; APX; APE1; APEN; APEX; HAP1; REF1
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis; by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
- Gene Details:
- apurinic/apyrimidinic endodeoxyribonuclease 1
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human APE1. The exact sequence is proprietary.
- Isotype:
- IgG
- Protein Details:
- DNA-(apurinic or apyrimidinic site) lyase
- Purification:
- Purified by antigen-affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
