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Antibodies

TIGAR Antibody - C-terminal region

Product Sizes
100ul
£630.00
OAGA03600-100UL
About this Product
SKU:
OAGA03600
Additional Names:
FR2BP; C12orf5
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2;6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region.
Gene Details:
TP53 induced glycolysis regulatory phosphatase
Host:
Rabbit
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TIGAR. The exact sequence is proprietary.
Isotype:
IgG
Protein Details:
fructose-2;6-bisphosphatase TIGAR
Purification:
Purified by antigen-affinity chromatography.
Shipping Conditions:
Blue Ice
Storage Conditions:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody