ACVR1 Antibody
Product Sizes
100ul
£630.00
OAGA03298-100UL
About this Product
- SKU:
- OAGA03298
- Additional Names:
- FOP; ALK2; SKR1; TSRI; ACTRI; ACVR1A; ACVRLK2
- Clonality:
- Polyclonal
- Concentration:
- 0.41 mg/ml
- Extra Details:
- Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins; composed of a ligand-binding extracellular domain with cysteine-rich region; a transmembrane domain; and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding; resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.
- Gene Details:
- activin A receptor type 1
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human Activin A Receptor type I. The exact sequence is proprietary.
- Isotype:
- IgG
- Protein Details:
- activin receptor type-1
- Purification:
- Purified by antigen-affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
