MAP2K3 Antibody
Product Sizes
100ul
£630.00
OAGA02969-100UL
About this Product
- SKU:
- OAGA02969
- Additional Names:
- MEK3; MKK3; MAPKK3; PRKMK3; SAPKK2; SAPKK-2
- Clonality:
- Polyclonal
- Concentration:
- 0.66 mg/ml
- Extra Details:
- The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress; and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin; and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase; which thus leads to the constitutive activation of MAPK14; and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene.
- Gene Details:
- mitogen-activated protein kinase kinase 3
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human MEK3. The exact sequence is proprietary.
- Isotype:
- IgG
- Protein Details:
- dual specificity mitogen-activated protein kinase kinase 3
- Purification:
- Purified by antigen-affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
