HLA-DPA1 Antibody
Product Sizes
100ul
£630.00
OAGA02295-100UL
About this Product
- SKU:
- OAGA02295
- Additional Names:
- DPA1; PLT1; HLADP; HLASB; DP(W3); DP(W4); HLA-DPA; HLA-DP1A; HLA-DPB1
- Clonality:
- Polyclonal
- Concentration:
- 1mg/ml
- Extra Details:
- HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain; both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes; dendritic cells; macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities; resulting in up to 4 different molecules.
- Gene Details:
- major histocompatibility complex; class II; DP alpha 1
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human HLA-DPA1. The exact sequence is proprietary.
- Isotype:
- IgG
- Purification:
- Purified by antigen-affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
