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Antibodies

NFKB2 Antibody - C-terminal region

Product Sizes
100ul
£630.00
OAGA01495-100UL
About this Product
SKU:
OAGA01495
Additional Names:
p52; p100; H2TF1; LYT10; CVID10; LYT-10; NF-kB2; p49/p100
Clonality:
Polyclonal
Concentration:
1mg/ml
Extra Details:
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas; some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
Gene Details:
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Host:
Rabbit
Immunogen:
Recombinant protein encompassing a sequence within the C-terminus region of human NFkB p100. The exact sequence is proprietary.
Isotype:
IgG
Purification:
Purified by antigen-affinity chromatography.
Shipping Conditions:
Blue Ice
Storage Conditions:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody