APAF1 Antibody - C-terminal region
Product Sizes
100ul
£630.00
OAGA01456-100UL
About this Product
- SKU:
- OAGA01456
- Additional Names:
- CED4; APAF-1
- Clonality:
- Polyclonal
- Concentration:
- 0.51mg/ml
- Extra Details:
- This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain; a caspase recruitment domain (CARD); and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP; this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein; releasing its mature; activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.
- Gene Details:
- apoptotic peptidase activating factor 1
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human APAF1. The exact sequence is proprietary.
- Isotype:
- IgG
- Purification:
- Purified by antigen-affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
