TLR9 Antibody - N-terminal region
Product Sizes
100ul
£630.00
OAGA01382-100UL
About this Product
- SKU:
- OAGA01382
- Additional Names:
- CD289
- Clonality:
- Polyclonal
- Concentration:
- 0.4mg/ml
- Extra Details:
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents; and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues; such as spleen; lymph node; bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
- Gene Details:
- toll-like receptor 9
- Host:
- Rabbit
- Immunogen:
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human TLR9. The exact sequence is proprietary.
- Isotype:
- IgG
- Purification:
- Purified by antigen-affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
