ABAT Antibody
Product Sizes
100ul
£630.00
OAGA01301-100UL
About this Product
- SKU:
- OAGA01301
- Additional Names:
- GABAT; NPD009; GABA-AT
- Clonality:
- Polyclonal
- Concentration:
- 1mg/ml
- Extra Details:
- 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA); an important; mostly inhibitory neurotransmitter in the central nervous system; into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation; hypotonia; hyperreflexia; lethargy; refractory seizures; and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
- Gene Details:
- 4-aminobutyrate aminotransferase
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human ABAT. The exact sequence is proprietary.
- Isotype:
- IgG
- Purification:
- Purified by antigen-affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
