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Antibodies

APOE Antibody - C-terminal region

Product Sizes
100ul
£630.00
OAGA01162-100UL
About this Product
SKU:
OAGA01162
Additional Names:
AD2; LPG; APO-E; ApoE4; LDLCQ5
Clonality:
Polyclonal
Concentration:
0.66 mg/ml
Extra Details:
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor; and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia; or type III hyperlipoproteinemia (HLP III); in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple transcript variants.
Gene Details:
apolipoprotein E
Host:
Rabbit
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Apolipoprotein E. The exact sequence is proprietary.
Isotype:
IgG
Molecular Weight:
36 kDa
Purification:
Purified by antigen-affinity chromatography.
Shipping Conditions:
Blue Ice
Storage Conditions:
Keep as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks); store at 4°C. For long-term storage; aliquot and store at -20°C or below. Avoid multiple freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody