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Antibodies

AKAP12 antibody

Product Sizes
100ul
£630.00
OAGA00496-100UL
About this Product
SKU:
OAGA00496
Additional Names:
SSeCKS; AKAP250
Clonality:
Polyclonal
Concentration:
0.73 mg/ml
Extra Details:
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins; which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells; cultured fibroblasts; and osteosarcoma cells. It associates with protein kinases A and C and phosphatase; and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Gene Details:
A-kinase anchor protein 12
Host:
Rabbit
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human AKAP12. The exact sequence is proprietary.
Isotype:
IgG
Molecular Weight:
191 kDa
Protein Details:
A-kinase anchor protein 12
Purification:
Purified by antigen-affinity chromatography.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks); store at 4°C. For long-term storage; aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody