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Antibodies

BAX Antibody

Product Sizes
250ug
£532.00
OAEG00908-250UG
About this Product
SKU:
OAEG00908
Additional Names:
BCL2L4
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Bax-beta is encoded by a 1.5 kb RNA species created by the retention of intron 5 in the bax mRNA transcript. The exon4/intron5 splice junction is evolutionarily conserved and is found in both the human and mouse bax coding regions. The 630 bp intron 5 contributes 60 amino acids to the Bax-beta protein before a stop codon is encountered during translation. Although the Bax-beta protein contains the BH1; BH2; and BH3 domains identical to Bax; it has a unique carboxyl terminus and does not have a hydrophobic transmembrane domain. Bax-beta mRNA has been found in many mouse tissues using RT-PCR. It is found co-expressed with Bax-alpha in lung; stomach; kidney; thymus; lymph node; bone marrow; pancreas; and spleen. Bax-beta mRNA was very abundant in brain and duodenum with almost no Bax-alpha mRNA detected in these tissues
Gene Details:
Apoptosis regulator BAX
Host:
Sheep
Immunogen:
Synthetic peptide corresponding to amino acids 172 to 199 of the Bax-beta protein
Isotype:
IgG
Molecular Weight:
21 kDa
Purification:
Ammonium Sulfate Precipitation
Shipping Conditions:
Blue Ice
Storage Conditions:
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody