CD79A Antibody
Product Sizes
100 tests (T100)
£441.00
OAEE00967-100TESTS
About this Product
- SKU:
- OAEE00967
- Additional Names:
- B-cell antigen receptor complex-associated protein alpha chain;CD79a antigen (immunoglobulin-associated alpha);CD79a molecule; immunoglobulin-associated alpha;IGA;ig-alpha;MB-1;MB-1 membrane glycoprotein;membrane-bound immunoglobulin-associated protein;surface IgM-associated protein.
- translate.label.attr.clone:
- HM47
- Clonality:
- Monoclonal
- Conjugate:
- R-PE
- Concentration:
- 10 ul / test
- Extra Details:
- Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex; trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK; bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
- Gene Details:
- CD79a molecule
- Host:
- Mouse
- Immunogen:
- Synthetic peptide corresponding to C terminal amino acids 208-222 of human CD79a
- Isotype:
- IgG1
- Protein Details:
- B-cell antigen receptor complex-associated protein alpha chain
- Purification:
- Purified by size-exclusion chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
