CD6 Antibody
Product Sizes
100 tests (T100)
£441.00
OAEE00932-100TESTS
About this Product
- SKU:
- OAEE00932
- Additional Names:
- CD6 antigen;T12;T-cell differentiation antigen CD6;TP120.
- translate.label.attr.clone:
- MEM-98
- Clonality:
- Monoclonal
- Conjugate:
- R-PE
- Concentration:
- 20 ul / test
- Extra Details:
- Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166 (PubMed:15048703; PubMed:15294938; PubMed:16352806; PubMed:16914752; PubMed:24945728; PubMed:24584089). Contributes to signaling cascades triggered by activation of the TCR/CD3 complex (PubMed:24584089). Functions as costimulatory molecule; promotes T-cell activation and proliferation (PubMed:15294938; PubMed:16352806; PubMed:16914752). Contributes to the formation and maturation of the immunological synapse (PubMed:15294938; PubMed:16352806). Functions as calcium-dependent pattern receptor that binds and aggregates both Gram-positive and Gram-negative bacteria. Binds both lipopolysaccharide (LPS) from Gram-negative bacteria and lipoteichoic acid from Gram-positive bacteria (PubMed:17601777). LPS binding leads to the activation of signaling cascades and down-stream MAP kinases (PubMed:17601777). Mediates activation of the inflammatory response and the secretion of pro-inflammatory cytokines in response to LPS (PubMed:17601777).
- Gene Details:
- CD6 molecule
- Host:
- Mouse
- Immunogen:
- Human CD6 antigen purified by immunoaffinity chromatography from HBP-ALL cells followed by preparative SDS-PAGE of non-boiled non-reduced sample (excised piece of gel corresponding to the 100 kDa zone).
- Isotype:
- IgG1
- Protein Details:
- T-cell differentiation antigen CD6
- Purification:
- Purified by size-exclusion chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
