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Antibodies

CD6 Antibody

Product Sizes
CD6 Antibody
£ POA
OAEE00932
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
OAEE00932
Application:
Flow Cytometry, Immunoprecipitation, Western Blot, IHC-Paraffin
Clone:
MEM-98
Clonality:
Monoclonal
Concentration:
20 ul / test
Formulation:
PE
Gene Details:
CD6
Host:
Mouse
Isotype:
IgG1
Protein Details:
T-cell differentiation antigen CD6
Purification:
Purified by size-exclusion chromatography
References:
Bazil V. et al: Monoclonal antibodies against human leucocyte antigens. III. Antibodies against CD45R, CD6, CD44 and two newly described broadly expressed glycoproteins MEM-53 and MEM-102. Folia Biol. (Praha) 35, 35 (1989). <br/>Castro MA, Oliveira MI, Nunes RJ, Fabre S, Barbosa R, Peixoto A, Brown MH, Parnes JR, Bismuth G, Moreira A, Rocha B, Carmo AM: Extracellular isoforms of CD6 generated by alternative splicing regulate targeting of CD6 to the immunological synapse. J Immunol. 2007 Apr 1;178(7):4351-61.<br/>Hassan NJ, Simmonds SJ, Clarkson NG, Hanrahan S, Puklavec MJ, Bomb M, Barclay AN, Brown MH: CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76. Mol Cell Biol. 2006 Sep;26(17):6727-38.<br/>Zimmerman AW, Joosten B, Torensma R, Parnes JR, van Leeuwen FN, Figdor CG.: Long-term engagement of CD6 and ALCAM is essential for T-cell proliferationinduced by dendritic cells. Blood. 2006 Apr 15;107(8):3212-20. Epub 2005 Dec 13.<br/>Osorio LM, De Santiago A, Aguilar-Santelises M, Mellstedt H, Jondal M.: CD6 ligation modulates the Bcl-2/Bax ratio and protects chronic lymphocyticleukemia B cells from apoptosis induced by anti-IgM. Blood. 1997 Apr 15;89(8):2833-41.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store in the dark at 2-8C. Do not freeze. Avoid prolonged exposure to light.
Do not use after expiration date stamped on vial label.
Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.
Supplier:
Aviva Systems Biology
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