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Antibodies

ITGA2B Antibody

Product Sizes
100 tests (T100)
£441.00
OAEE00856-100TESTS
About this Product
SKU:
OAEE00856
Additional Names:
alphaIIb protein;BDPLT16;BDPLT2;CD41;CD41B;GP2B;GPalpha IIb;GPIIb;GT;GT1;GTA;HPA3;integrin alpha-IIb;integrin; alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex; antigen CD41);platelet fibrinogen receptor; alpha subunit;platelet glycoprotein IIb of IIb/IIIa complex;platelet membrane glycoprotein IIb;platelet-specific antigen BAK;PPP1R93;protein phosphatase 1; regulatory subunit 93.
translate.label.attr.clone:
MEM-06
Clonality:
Monoclonal
Conjugate:
APC
Concentration:
10 ul / test
Extra Details:
Integrin alpha-IIb/beta-3 is a receptor for fibronectin; fibrinogen; plasminogen; prothrombin; thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
Gene Details:
integrin subunit alpha 2b
Host:
Mouse
Immunogen:
Leukocytes of patient suffering from LGL-type leukaemia.
Isotype:
IgG1
Protein Details:
Integrin alpha-IIb
Purification:
Purified by size-exclusion chromatography
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody