TNFRSF10B Antibody
Product Sizes
0.1 mg (C100)
£511.00
OAEE00758-0.1MG
About this Product
- SKU:
- OAEE00758
- Additional Names:
- apoptosis inducing protein TRICK2A/2B;apoptosis inducing receptor TRAIL-R2;CD262;cytotoxic TRAIL receptor-2;death domain containing receptor for TRAIL/Apo-2L;death receptor 5;DR5;Fas-like protein;KILLER;KILLER/DR5;p53-regulated DNA damage-inducible cell death receptor(killer);TNF-related apoptosis-inducing ligand receptor 2;TRAILR2;TRAIL-R2;TRICK2;TRICK2A;TRICK2B;TRICKB;tumor necrosis factor receptor superfamily member 10B;tumor necrosis factor receptor superfamily; member 10b;tumor necrosis factor receptor-like protein ZTNFR9;ZTNFR9.
- translate.label.attr.clone:
- DR5-01-1
- Clonality:
- Monoclonal
- Conjugate:
- FITC
- Concentration:
- 0.1 mg/ml
- Extra Details:
- Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:10549288). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
- Gene Details:
- TNF receptor superfamily member 10b
- Host:
- Mouse
- Immunogen:
- Recombinant fusion protein of human IgG heavy chain and extracellular domain of DR5.
- Isotype:
- IgG1
- Protein Details:
- Tumor necrosis factor receptor superfamily member 10B
- Purification:
- Purified by size-exclusion chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
