FASLG Antibody
Product Sizes
100 tests (T100)
£441.00
OAEE00681-100TESTS
About this Product
- SKU:
- OAEE00681
- Additional Names:
- ALPS1B;apoptosis (APO-1) antigen ligand 1;apoptosis antigen ligand;APT1LG1;APTL;CD178;CD95 ligand;CD95L;CD95-L;fas antigen ligand;Fas ligand (TNF superfamily; member 6);FASL;mutant tumor necrosis factor family member 6;TNFSF6;TNLG1A;tumor necrosis factor ligand 1A;tumor necrosis factor ligand superfamily member 6.
- translate.label.attr.clone:
- NOK-1
- Clonality:
- Monoclonal
- Conjugate:
- R-PE
- Concentration:
- 10 ul / test
- Extra Details:
- Cytokine that binds to TNFRSF6/FAS; a receptor that transduces the apoptotic signal into cells (PubMed:26334989; PubMed:9228058). Involved in cytotoxic T-cell-mediated apoptosis; natural killer cell-mediated apoptosis and in T-cell development (PubMed:9228058; PubMed:7528780; PubMed:9427603). Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses (By similarity). TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance (By similarity). Binds to TNFRSF6B/DcR3; a decoy receptor that blocks apoptosis (PubMed:27806260).
- Gene Details:
- Fas ligand
- Host:
- Mouse
- Immunogen:
- L5178Y mouse T lymphoma cells expressing recombinant human CD178
- Isotype:
- IgG1
- Protein Details:
- Tumor necrosis factor ligand superfamily member 6
- Purification:
- Purified by size-exclusion chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
