CD40LG Antibody
Product Sizes
0.1 mg (C100)
£337.00
OAEE00658-0.1MG
About this Product
- SKU:
- OAEE00658
- Additional Names:
- CD154;CD40 antigen ligand;CD40 ligand;CD40L;CD40-L;gp39;hCD40L;HIGM1;IGM;IMD3;T-B cell-activating molecule;T-BAM;T-cell antigen Gp39;TNF-related activation protein;TNFSF5;TRAP;tumor necrosis factor (ligand) superfamily member 5;Tumor necrosis factor ligand superfamily member 5.
- translate.label.attr.clone:
- MR-1
- Clonality:
- Monoclonal
- Conjugate:
- FITC
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Cytokine that binds to CD40/TNFRSF5 (PubMed:1280226). Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (PubMed:8617933). Induces the activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells. Induces tyrosine phosphorylation of isoform 3 of CD28 (PubMed:15067037). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching (By similarity).
- Gene Details:
- CD40 ligand
- Host:
- Hamster
- Immunogen:
- Activated mouse Th1 clone D1.6
- Isotype:
- IgG1
- Protein Details:
- CD40 ligand
- Purification:
- Purified by size-exclusion chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
