ITGAL Antibody
Product Sizes
100 tests (T100)
£398.00
OAEE00608-100TESTS
About this Product
- SKU:
- OAEE00608
- Additional Names:
- antigen CD11A (p180); lymphocyte function-associated antigen 1; alpha polypeptide;CD11 antigen-like family member A;CD11A;integrin alpha-L;integrin gene promoter;integrin; alpha L (antigen CD11A (p180); lymphocyte function-associated antigen 1; alpha polypeptide);leukocyte adhesion glycoprotein LFA-1 alpha chain;leukocyte function-associated molecule 1 alpha chain;LFA-1;LFA-1 alpha;LFA1A;LFA-1A;lymphocyte function-associated antigen 1; alpha polypeptide.
- translate.label.attr.clone:
- MEM-25
- Clonality:
- Monoclonal
- Conjugate:
- FITC
- Concentration:
- 20 ul / test
- Extra Details:
- Integrin alpha-L/beta-2 is a receptor for ICAM1; ICAM2; ICAM3 and ICAM4. Integrin alpha-L/beta-2 is also a receptor for F11R (PubMed:11812992; PubMed:15528364). Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction; cytotoxic T-cell mediated killing; and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity (PubMed:15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed:11812992). Required for generation of common lymphoid progenitor cells in bone marrow; indicating a role in lymphopoiesis (By similarity). Integrin alpha-L/beta-2 in association with ICAM3; contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590).
- Gene Details:
- integrin subunit alpha L
- Host:
- Mouse
- Immunogen:
- Leukocytes from a patient suffering from a LGL-type leukaemia.
- Isotype:
- IgG1
- Protein Details:
- Integrin alpha-L
- Purification:
- Purified by size-exclusion chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
