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Antibodies

CD101 Antibody

Product Sizes
100 tests (T100)
£441.00
OAEE00585-100TESTS
About this Product
SKU:
OAEE00585
Additional Names:
cell surface glycoprotein V7;EWI-101;glu-Trp-Ile EWI motif-containing protein 101;IGSF2;immunoglobulin superfamily member 2;leukocyte surface protein;V7.
translate.label.attr.clone:
BB27
Clonality:
Monoclonal
Conjugate:
R-PE
Concentration:
10 ul / test
Extra Details:
Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.
Gene Details:
CD101 molecule
Host:
Mouse
Immunogen:
Human thymic clone B12
Isotype:
IgG1
Protein Details:
Immunoglobulin superfamily member 2
Purification:
Purified by size-exclusion chromatography
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody