BCL2 Antibody
Product Sizes
100 tests (T100)
£500.00
OAEE00572-100TESTS
About this Product
- SKU:
- OAEE00572
- Additional Names:
- apoptosis regulator Bcl-2;B-cell CLL/lymphoma 2;Bcl-2;PPP1R50;protein phosphatase 1; regulatory subunit 50.
- translate.label.attr.clone:
- Bcl2/100
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Concentration:
- 10 ul / test
- Extra Details:
- Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation; hence CASP1 activation and IL1B release (PubMed:17418785).
- Gene Details:
- BCL2 apoptosis regulator
- Host:
- Mouse
- Immunogen:
- Synthetic peptide corresponding to the amino acids 41-54 of human Bcl2
- Isotype:
- IgG1
- Protein Details:
- Apoptosis regulator Bcl-2
- Purification:
- Purified by size-exclusion chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
