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Antibodies

GZMB Antibody

Product Sizes
0.1 mg (C100)
£376.00
OAEE00403-0.1MG
About this Product
SKU:
OAEE00403
Additional Names:
C11;cathepsin G-like 1;CCPI;CGL1;CGL-1;CSPB;CSP-B;CTLA1;CTLA-1;CTSGL1;cytotoxic serine protease B;cytotoxic T-lymphocyte proteinase 2;fragmentin 2;Fragmentin-2;granzyme B;granzyme B (granzyme 2; cytotoxic T-lymphocyte-associated serine esterase 1);Granzyme-2;HLP;human lymphocyte protein;SECT;T-cell serine protease 1-3E.
translate.label.attr.clone:
CLB-GB11
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3; -7; -9 and 10 to give rise to active enzymes mediating apoptosis.
Gene Details:
granzyme B
Host:
Mouse
Immunogen:
Human NK cell line YT-INDY-derived granzyme B
Isotype:
IgG1
Protein Details:
Granzyme B
Purity:
> 95% (by SDS-PAGE)
Purification:
Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody