CD6 Antibody
Product Sizes
CD6 Antibody
£ POA
OAEE00288
About this Product
- SKU:
- OAEE00288
- Application:
- Flow Cytometry, Immunoprecipitation, Western Blot, IHC-Paraffin
- Clone:
- MEM-98
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Formulation:
- Purified
- Gene Details:
- CD6
- Host:
- Mouse
- Isotype:
- IgG1
- Protein Details:
- T-cell differentiation antigen CD6
- Purity:
- > 95% (by SDS-PAGE)
- Purification:
- Purified by protein A
- References:
- Bazil V. et al: Monoclonal antibodies against human leucocyte antigens. III. Antibodies against CD45R, CD6, CD44 and two newly described broadly expressed glycoproteins MEM-53 and MEM-102. Folia Biol. (Praha) 35, 35 (1989). <br/>Castro MA, Oliveira MI, Nunes RJ, Fabre S, Barbosa R, Peixoto A, Brown MH, Parnes JR, Bismuth G, Moreira A, Rocha B, Carmo AM: Extracellular isoforms of CD6 generated by alternative splicing regulate targeting of CD6 to the immunological synapse. J Immunol. 2007 Apr 1;178(7):4351-61.<br/>Hassan NJ, Simmonds SJ, Clarkson NG, Hanrahan S, Puklavec MJ, Bomb M, Barclay AN, Brown MH: CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76. Mol Cell Biol. 2006 Sep;26(17):6727-38.<br/>Zimmerman AW, Joosten B, Torensma R, Parnes JR, van Leeuwen FN, Figdor CG.: Long-term engagement of CD6 and ALCAM is essential for T-cell proliferationinduced by dendritic cells. Blood. 2006 Apr 15;107(8):3212-20. Epub 2005 Dec 13.<br/>Osorio LM, De Santiago A, Aguilar-Santelises M, Mellstedt H, Jondal M.: CD6 ligation modulates the Bcl-2/Bax ratio and protects chronic lymphocyticleukemia B cells from apoptosis induced by anti-IgM. Blood. 1997 Apr 15;89(8):2833-41.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8C. Do not freeze. Do not use after expiration date stamped on vial label.
- Supplier:
- Aviva Systems Biology
- Manufacturer's Data Sheet:html_datasheet.php
