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Antibodies

CD47 Antibody

Product Sizes
0.1 mg (C100)
£337.00
OAEE00261-0.1MG
About this Product
SKU:
OAEE00261
Additional Names:
antigen identified by monoclonal antibody 1D8;antigenic surface determinant protein OA3;CD47 antigen (Rh-related antigen; integrin-associated signal transducer);CD47 glycoprotein;IAP;integrin associated protein;Integrin-associated protein;integrin-associated signal transducer;leukocyte surface antigen CD47;MER6;OA3;Protein MER6;Rh-related antigen.
translate.label.attr.clone:
MEM-122
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets; and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA; binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion; enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
Gene Details:
CD47 molecule
Host:
Mouse
Immunogen:
COS-7 (African green monkey) cells
Isotype:
IgM
Protein Details:
Leukocyte surface antigen CD47
Purity:
> 95% (by SDS-PAGE)
Purification:
Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody