CD22 Antibody
Product Sizes
0.1 mg (C100)
£326.00
OAEE00152-0.1MG
About this Product
- SKU:
- OAEE00152
- Additional Names:
- B-cell receptor CD22;BL-CAM;B-lymphocyte cell adhesion molecule;CD22 antigen;sialic acid-binding Ig-like lectin 2;SIGLEC2;SIGLEC-2;T-cell surface antigen Leu-14.
- translate.label.attr.clone:
- IS7
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2;6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
- Gene Details:
- CD22 molecule
- Host:
- Mouse
- Immunogen:
- human cell line Reh
- Isotype:
- IgG1
- Protein Details:
- B-cell receptor CD22
- Purity:
- > 95% (by SDS-PAGE)
- Purification:
- Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
