ITGB2 Antibody
Product Sizes
0.1 mg (C100)
£326.00
OAEE00117-0.1MG
About this Product
- SKU:
- OAEE00117
- Additional Names:
- CD18;CD18 subunit;cell surface adhesion glycoproteins LFA-1/CR3/p150;95 subunit beta;complement receptor C3 subunit beta;integrin beta-2;integrin; beta 2 (antigen CD18 subunit (p95); lymphocyte function-associated antigen 1; integrin B2);integrin; beta 2 (complement component 3 receptor 3 and 4 subunit);Leu-CAM receptor;leukocyte surface protein.
- translate.label.attr.clone:
- IVA35
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Integrin alpha-L/beta-2 is a receptor for ICAM1; ICAM2; ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity. Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. Integrin alpha-L/beta-2 in association with ICAM3; contributes to apoptotic neutrophil phagocytosis by macrophages.
- Gene Details:
- integrin subunit beta 2
- Host:
- Mouse
- Immunogen:
- Bovine leukocytes.
- Isotype:
- IgG1
- Protein Details:
- Integrin beta-2
- Purity:
- > 95% (by SDS-PAGE)
- Purification:
- Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
