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Antibodies

ITGAM Antibody

Product Sizes
0.1 mg (C100)
£246.00
OAEE00072-0.1MG
About this Product
SKU:
OAEE00072
Additional Names:
CD11 antigen-like family member B;Cd11b;CD11B (p170);CD11b/CD18;cell surface glycoprotein MAC-1 alpha subunit;cell surface glycoprotein MAC-1 subunit alpha;complement receptor type 3;CR;CR3;CR-3 alpha chain;CR3A;F730045J24Rik;integrin alpha-M;leukocyte adhesion receptor MO1;Ly-4;Ly-40;Mac-;Mac-1;MAC1;Mac-1 alpha;Mac-1a;macrophage antigen alpha.
translate.label.attr.clone:
M1/70
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
CD11b (integrin alphaM subunit) is a 165-170 kDa type I transmembrane glycoprotein that non-covalently associates with integrin beta2 subunit (CD18); expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin (Mac-1; CR3) is highly expressed on NK cells; neutrophils; monocytes and less on macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes; macrophages and granulocytes; facilitating their diapedesis; as well as it mediates the uptake of complement coated particles; serving as a receptor for the iC3b fragment of the third complement component.
Gene Details:
integrin alpha M
Host:
Rat
Immunogen:
B10 mouse spleen cells enriched for T cells
Isotype:
IgG2b
Protein Details:
Integrin alpha-M
Purity:
> 95% (by SDS-PAGE)
Purification:
Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody