CD11b antibody
Product Sizes
0.1 mg (C100)
£326.00
OAEE00068-0.1MG
About this Product
- SKU:
- OAEE00068
- Additional Names:
- antigen CD11b (p170);CD11 antigen-like family member B;CD11B;cell surface glycoprotein MAC-1 subunit alpha;complement component 3 receptor 3 subunit;CR-3 alpha chain;CR3A;integrin alpha-M;integrin; alpha M (complement component 3 receptor 3 subunit);leukocyte adhesion receptor MO1;MAC-1;MAC1A;macrophage antigen alpha polypeptide;macrophage-1 antigen alpha subunit;MO1A;Neutrophil adherence receptor;neutrophil adherence receptor alpha-M subunit;SLEB6.
- translate.label.attr.clone:
- MEM-174
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes; macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3; the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen; factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration (PubMed:28807980). In association with beta subunit ITGB2/CD18; required for CD177-PRTN3-mediated activation of TNF primed neutrophils (PubMed:21193407). May regulate phagocytosis-induced apoptosis in extravasated neutrophils (By similarity). May play a role in mast cell development (By similarity).
- Gene Details:
- integrin subunit alpha M
- Host:
- Mouse
- Immunogen:
- Human granulocytes
- Isotype:
- IgG2a
- Protein Details:
- Integrin alpha-M
- Purity:
- > 95% (by SDS-PAGE)
- Purification:
- Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
