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Antibodies

Anti-PIDD

Product Sizes
100 ug
£641.00
OAED00370-100UG
About this Product
SKU:
OAED00370
Additional Names:
leucine-rich repeat and death domain-containing protein;leucine-rich repeats and death domain containing;LRDD;p53-induced death domain-containing protein 1;p53-induced protein with a death domain;PIDD.
translate.label.attr.clone:
Anto-1
Clonality:
Monoclonal
Concentration:
1mg/ml
Extra Details:
Promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. Associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. Associates with CASP2/caspase-2 and CRADD/RAIDD; and induces activation of CASP2 which an important regulator in apoptotic pathways.
Gene Details:
p53-induced death domain protein 1
Host:
Mouse
Immunogen:
Recombinant human PIDD death domain (aa 776-910).
Isotype:
IgG1
Protein Details:
p53-induced death domain-containing protein 1
Purity:
≥95% (SDS-PAGE)
Shipping Conditions:
Blue Ice
Source:
Purified from concentrated hybridoma tissue culture supernatant.
Storage Conditions:
Long Term Storage : -20C
Short Term Storage : +4C
Handling : After opening; prepare aliquots and store at -20C.
Avoid freeze/thaw cycles
Stable for at least 1 year after receipt when stored at -20C.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody