Anti-SARM
Product Sizes
100 ug
£615.00
OAED00366-100UG
About this Product
- SKU:
- OAED00366
- Additional Names:
- hSARM1;HsTIR;MyD88-5;NAD(+) hydrolase SARM1;NADase SARM1;NADP(+) hydrolase SARM1;SAM domain-containing protein 2;SAMD2;SARM;sterile alpha and Armadillo repeat protein;sterile alpha and HEAT/Armadillo motif protein; ortholog of Drosophila;sterile alpha and TIR motif-containing protein 1;sterile alpha motif domain-containing protein 2;tir-1 homolog.
- translate.label.attr.clone:
- Sarmy-1
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway which plays a pivotal role in activating axonal degeneration following injury. Promotes Wallerian degeneration an injury-induced axonal death pathway which involves degeneration of an axon distal to the injury site. Can activate neuronal death in response to stress. Regulates dendritic arborization through the MAPK4-JNK pathway. Involved in innate immune response. Inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1; TRIF-dependent activation of NF-kappa-B and IRF3; and the phosphorylation of MAPK14/p38.
- Gene Details:
- sterile alpha and TIR motif containing 1
- Host:
- Mouse
- Immunogen:
- Recombinant human SARM (aa 93-292).
- Isotype:
- IgG2b
- Protein Details:
- Sterile alpha and TIR motif-containing protein 1
- Purification:
- Purified from concentrated hybridoma tissue culture supernatant
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store short-term at 4°C and long-term at -20°C. Stable for at least 1 year after receipt when stored at -20°C.
Avoid freeze/thaw cycles. - Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
