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Antibodies

Anti-APRIL

Product Sizes
100 ug
£647.00
OAED00345-100UG
About this Product
SKU:
OAED00345
Additional Names:
30 kDa adipocyte complement-related protein;a proliferation-inducing ligand;ACDC;ACRP30;adipocyte complement-related 30 kDa protein;Adipocyte; C1q and collagen domain-containing protein;adiponectin;adipose most abundant gene transcript 1 protein;adipose specific collagen-like factor;ADIPQTL1;ADPN;APM1;APM-1;APRIL;CD256;GBP28;Gelatin-binding protein;gelatin-binding protein 28;TALL2;TALL-2;TNF- and APOL-related leukocyte expressed ligand 2;TNF-related death ligand 1;TNLG7B;TRDL-1;tumor necrosis factor (ligand) superfamily; member 13;tumor necrosis factor ligand 7B;tumor necrosis factor ligand superfamily member 13;tumor necrosis factor superfamily member 13;tumor necrosis factor-like protein ZTNF2;tumor necrosis factor-related death ligand-1;UNQ383/PRO715;ZTNF2.
translate.label.attr.clone:
Sacha-2
Clonality:
Monoclonal
Concentration:
1mg/ml
Extra Details:
Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.|Important adipokine involved in the control of fat metabolism and insulin sensitivity; with direct anti-diabetic; anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle; enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages; and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth; angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities; depending on the type of complex; LMW; MMW or HMW.
Gene Details:
adiponectin; C1Q and collagen domain containing|TNF superfamily member 13
Host:
Rat
Immunogen:
Recombinant human APRIL (aa 105-250) fused to human ACRP30headless (aa 16-108) (Prod. No. ALX-522-035).
Isotype:
IgG2a
Protein Details:
Adiponectin|Tumor necrosis factor ligand superfamily member 13
Purity:
≥95% (SDS-PAGE)
Shipping Conditions:
Blue Ice
Source:
Purified from concentrated hybridoma tissue culture supernatant.
Storage Conditions:
Long Term Storage : +4C
Handling : Do not freeze/thaw.
Stable for at least 6 months after receipt when stored at +4C undiluted.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody