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Antibodies

Anti-Tollip

Product Sizes
100 ug
£684.00
OAED00322-100UG
About this Product
SKU:
OAED00322
Additional Names:
4930403G24Rik;4931428G15Rik;toll-interacting protein.
translate.label.attr.clone:
Kimmy-2
Clonality:
Monoclonal
Concentration:
1mg/ml
Extra Details:
Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity. Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (By similarity).
Gene Details:
toll interacting protein
Host:
Mouse
Immunogen:
Recombinant mouse Tollip (aa 1-274).
Isotype:
IgG1
Protein Details:
Toll-interacting protein
Purity:
95% (SDS-PAGE)
Shipping Conditions:
Blue Ice
Source:
Purified from concentrated hybridoma tissue supernatant.
Storage Conditions:
Long Term Storage : -20C
Short Term Storage : +4C
Handling : Avoid freeze/thaw cycles.
Stable for at least 1 year after receipt when stored as recommended.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody