Anti-FasL
Product Sizes
100 ug
£576.00
OAED00293-100UG
About this Product
- SKU:
- OAED00293
- Additional Names:
- APT1;APT1LG1;CD178;CD95;CD95 ligand;CD95L;CD95-L;F;Fa;Fas antigen ligand;Fas-L;Faslg;generalized lymphoproliferative disease;gld;Tnfs;Tnfsf6;Tnlg1a;tumor necrosis factor ligand 1a;tumor necrosis factor ligand superfamily member 6.
- translate.label.attr.clone:
- H11
- Clonality:
- Monoclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1mg/ml
- Extra Details:
- Cytokine that binds to TNFRSF6/FAS; a receptor that transduces the apoptotic signal into cells (PubMed:7511063). Involved in cytotoxic T-cell-mediated apoptosis; natural killer cell-mediated apoptosis and in T-cell development (PubMed:19794494; PubMed:7532682). Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses (PubMed:19794494). TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance (PubMed:10779162). Binds to TNFRSF6B/DcR3; a decoy receptor that blocks apoptosis (By similarity).
- Gene Details:
- Fas ligand (TNF superfamily; member 6)
- Host:
- Rat
- Immunogen:
- Synthetic peptide corresponding to aa 196-220 of mouse FasL (CD95L; APO-1L; CD178).
- Isotype:
- IgG2a
- Protein Details:
- Tumor necrosis factor ligand superfamily member 6
- Purity:
- ≥95% (SDS-PAGE).
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Long Term Storage : +4C
Handling : Do not freeze/thaw.
Stable for at least 6 months after receipt when stored at +4C undiluted. - Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
