DLG4 Antibody
Product Sizes
100 ug
£539.00
OAED00229-100UG
About this Product
- SKU:
- OAED00229
- Additional Names:
- discs large homolog 4;discs; large homolog 4;disks large homolog 4;Dlgh;Dlgh4;postsynaptic density protein 95;PSD;PSD-;PSD95;PSD-95;PSD-95 alpha 2b;PSD-95 beta;SA;SAP90;SAP-90;SAP90A;synapse-associated protein 90.
- translate.label.attr.clone:
- 7E3-1B8
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression (Probable).
- Gene Details:
- discs large MAGUK scaffold protein 4
- Host:
- Mouse
- Immunogen:
- Recombinant rat PSD-95.
- Isotype:
- IgG2a
- Protein Details:
- Disks large homolog 4
- Purification:
- Protein G affinity purified.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Shipped on Blue Ice. For long term storage; store at -20C.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
