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Antibodies

Anti-DnaJ

Product Sizes
50 ug
£348.00
OAED00145-50UG
About this Product
SKU:
OAED00145
Additional Names:
b0015;chaperone protein DnaJ;ECK0015;groP;grpC;Heat shock protein J;HSP40.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Interacts with DnaK and GrpE to disassemble a protein complex at the origins of replication of phage lambda and several plasmids. Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins; also in an autonomous; DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein; DnaK hydrolyzes its bound ATP; resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein; thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ; DnaK and GrpE are required for fully efficient folding.
Gene Details:
chaperone protein DnaJ
Host:
Rabbit
Immunogen:
E. coli DnaJ.
Molecular Weight:
~41kDa
Protein Details:
Chaperone protein DnaJ
Purification:
Protein A affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
Ships with blue ice
Long Term Storage: -20°C
Avoid freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody