grpE Antibody
Product Sizes
1 mg
£2353.00
OAED00141-1MG
About this Product
- SKU:
- OAED00141
- Additional Names:
- b2614;ECK2610;Heat shock protein B25.3;HSP24;HSP-70 cofactor;nucleotide exchange factor GrpE.
- Clonality:
- Polyclonal
- Extra Details:
- Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein; DnaK hydrolyzes its bound ATP; resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein; thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ; DnaK and GrpE are required for fully efficient folding.
- Gene Details:
- nucleotide exchange factor GrpE
- Host:
- Rabbit
- Immunogen:
- Purified E. coli GrpE.
- Protein Details:
- Protein GrpE
- Purity:
- Protein A affinity purified.<br/>
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Long Term Storage : -20C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
