Anti-PDK1 Antibody
Product Sizes
50 ug
£348.00
OAED00097-50UG
About this Product
- SKU:
- OAED00097
- Additional Names:
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1; mitochondrial;mitochondrial pyruvate dehydrogenase; lipoamide; kinase isoenzyme 1;PDH kinase 1;pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1; mitochondrial;Pyruvate dehydrogenase kinase isoform 1;pyruvate dehydrogenase kinase; isoenzyme 1.
- Clonality:
- Polyclonal
- Extra Details:
- Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity; and thereby regulates metabolite flux through the tricarboxylic acid cycle; down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress.
- Gene Details:
- pyruvate dehydrogenase kinase 1
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to a portion of human PDK1 (Pyruvate dehydrogenase kinase-1).
- Protein Details:
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1; mitochondrial
- Purification:
- Protein A affinity purified.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Long Term Storage : -20C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
