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Antibodies

Caspase-3 Antibody

Product Sizes
50 ug
£348.00
OAED00052-50UG
About this Product
SKU:
OAED00052
Additional Names:
apopain;CASP-3;caspase 3; apoptosis-related cysteine peptidase;caspase 3; apoptosis-related cysteine protease;caspase-3;CPP32;CPP-32;CPP32B;cysteine protease CPP32;PARP cleavage protease;procaspase3;protein Yama;SCA-1;SREBP cleavage activity 1.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6; -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
Gene Details:
caspase 3
Host:
Rabbit
Immunogen:
Synthetic peptide corresponding to a portion of human caspase-3 . The sequence differs from rat caspase-3 by 1 aa and from mouse by 2 aa.
Molecular Weight:
~36 kDa
Protein Details:
Caspase-3
Shipping Conditions:
Blue Ice
Storage Conditions:
Long term storage at -20C. Avoid freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody