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Antibodies

Anti-Caspase-9

Product Sizes
100 ug
£576.00
OAED00020-100UG
About this Product
SKU:
OAED00020
Additional Names:
MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6
Clonality:
Monoclonal
Extra Details:
The caspases are a family of cysteine proteases that cleave after certain aspartate residues; and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or executioner caspases (e.g. caspase-3; -6; and -7) in a cascade-like manner; which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.
Host:
Mouse
Immunogen:
Recombinant full length human Caspase-9.
Isotype:
IgG2a
Protein Details:
Caspase-9
Purity:
Protein G affinity purified.<br/>
Shipping Conditions:
Blue Ice
Storage Conditions:
Long Term Storage : -20C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody