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Antibodies

AGR2 Antibody

Product Sizes
100 ug
£539.00
OAEB01151-100UG
About this Product
SKU:
OAEB01151
Additional Names:
AG2;AG-2;Agr2h;anterior gradient 2 homolog;anterior gradient homolog 2;anterior gradient protein 2 homolog;epididymis secretory protein Li 116;Gob-;GOB-4;HAG-;HAG-2;HEL-S-116;HPC8;mAG-;mAG-2;PDIA17;protein disulfide isomerase family A; member 17;protein Gob-4;secreted cement gland homolog;secreted cement gland protein XAG-2 homolog;XAG-;XAG-2.
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence; a catalytically active thioredoxin domain; and a C-terminal ER-retention sequence. This protein plays a role in cell migration; cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone; it plays a role in the folding; trafficking; and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression.
Gene Details:
anterior gradient 2|anterior gradient 2; protein disulphide isomerase family member
Host:
Goat
Immunogen:
AGR2
Protein Details:
Anterior gradient protein 2 homolog
Purification:
Ammonium Sulfate Precipitated; Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
Aliquot and store at -20C. Minimize freezing and thawing.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody