RUNX1T1 Antibody
Product Sizes
100ul
£597.00
OADC00048-100UL
About this Product
- SKU:
- OADC00048
- Additional Names:
- CDR; ETO; MTG8; AML1T1; ZMYND2; CBFA2T1; AML1-MTG8
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- Undetermined; ascites
- Extra Details:
- This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants.
- Gene Details:
- RUNX1 translocation partner 1
- Host:
- Rabbit
- Protein Details:
- protein CBFA2T1
- Purification:
- Whole antiserum
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
