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Antibodies

CD3 Antibody

Product Sizes
2 mL
£641.00
OADB00171-2ML
About this Product
SKU:
OADB00171
Additional Names:
T3D; IMD19; CD3-DELTA
translate.label.attr.clone:
B-B11
Clonality:
Monoclonal
Concentration:
200 tests/2mL
Extra Details:
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex; and along with four other CD3 subunits; binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist; but the full-length natures of their transcripts has yet to be defined.
Gene Details:
CD3d molecule
Host:
Human
Isotype:
Mouse IgG1
Molecular Weight:
19 kDa
Protein Details:
T-cell surface glycoprotein CD3 delta chain
Purification:
Ion exchange chromatography
Shipping Conditions:
Blue Ice
Storage Conditions:
Stable at +2-8C for 12 months. For longer storage; freeze aliquots
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody