CD253 Antibody - Biotin Conjugated
Product Sizes
1 mL
£608.00
OADB00135-1ML
About this Product
- SKU:
- OADB00135
- Additional Names:
- TL2; APO2L; CD253; TRAIL; Apo-2L; TNLG6A
- translate.label.attr.clone:
- B-S23
- Clonality:
- Monoclonal
- Conjugate:
- Biotin
- Concentration:
- 100 tests/1mL
- Extra Details:
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells; but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1; TNFRSF10B/TRAILR2; TNFRSF10C/TRAILR3; TNFRSF10D/TRAILR4; and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3; TNFRSF10D/TRAILR4; and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK; caspase 8; and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Gene Details:
- tumor necrosis factor superfamily member 10
- Host:
- Mouse
- Isotype:
- IgG1
- Molecular Weight:
- 33 kDa
- Protein Details:
- tumor necrosis factor ligand superfamily member 10
- Purification:
- Ion exchange chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Reconstitute with 1 mL deionised water
Use 10 uL to label 106 cells or 100 uL of whole blood. Stable at +2-8C for six months after reconstitution. For longer storage; freeze aliquots - Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
