CD130 Antibody
Product Sizes
200 ug
£608.00
OADB00048-200UG
About this Product
- SKU:
- OADB00048
- Additional Names:
- CD130; GP130; HIES4; CDW130; IL-6RB; sGP130
- translate.label.attr.clone:
- B-K5
- Clonality:
- Monoclonal
- Concentration:
- 1 ug/uL
- Extra Details:
- The protein encoded by this gene is a signal transducer shared by many cytokines; including interleukin 6 (IL6); ciliary neurotrophic factor (CNTF); leukemia inhibitory factor (LIF); and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6; a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus; can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
- Gene Details:
- interleukin 6 signal transducer
- Host:
- Mouse
- Isotype:
- IgG1
- Molecular Weight:
- 104 kDa
- Protein Details:
- interleukin-6 receptor subunit beta
- Purification:
- Ion exchange chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Stable at +2-8C for 12 months. For longer storage; freeze aliquots
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
