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Antibodies

UBR4 Antibody

Product Sizes
100ul
£359.00
OACD08109-100UL
1ml
£1020.00
OACD08109-1ML
About this Product
SKU:
OACD08109
Additional Names:
600 kDa retinoblastoma protein-associated factor;E3 ubiquitin-protein ligase UBR4;N-recognin-4;p600;RBAF600;retinoblastoma-associated factor 600-like protein;retinoblastoma-associated factor of 600 kDa;RING-type E3 ubiquitin transferase UBR4;zinc finger UBR1-type protein 1;ZUBR1.
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule; leading to their ubiquitination and subsequent degradation. Together with clathrin; forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Regulates integrin-mediated signaling. May play a role in activation of FAK in response to cell-matrix interactions. Mediates ubiquitination of ACLY; leading to its subsequent degradation.
Gene Details:
ubiquitin protein ligase E3 component n-recognin 4
Host:
Rabbit
Immunogen:
Range: Val124 - Arg396
Isotype:
IgG
Molecular Weight:
24 kDa
Protein Details:
E3 ubiquitin-protein ligase UBR4
Purification:
Affinity Purified; Protein A Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C|-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody