UBA52 Antibody
Product Sizes
100ul
£333.00
OACD08096-100UL
1ml
£933.00
OACD08096-1ML
About this Product
- SKU:
- OACD08096
- Additional Names:
- CEP52;HUBCEP52;L40;RPL40;Ubiquitin A-52 residue ribosomal protein fusion product 1;ubiquitin carboxyl extension protein 52;ubiquitin-52 amino acid fusion protein;ubiquitin-60S ribosomal protein L40;ubiquitin-CEP52.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Ubiquitin: Exists either covalently attached to another protein; or free (unanchored). When covalently bound; it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin); a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains; when attached to a target protein; have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis; DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins; however; in rare cases; conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin); it also has distinct roles; such as in activation of protein kinases; and in signaling.
- Gene Details:
- ubiquitin A-52 residue ribosomal protein fusion product 1
- Host:
- Rabbit
- Immunogen:
- Range: Met1 - Lys128
- Isotype:
- IgG
- Molecular Weight:
- 15 kDa
- Protein Details:
- Ubiquitin-60S ribosomal protein L40
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
