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Antibodies

TRADD Antibody

Product Sizes
100ul
£359.00
OACD08006-100UL
1ml
£1016.00
OACD08006-1ML
About this Product
SKU:
OACD08006
Additional Names:
Hs.89862;TNFR1-associated death domain protein;TNFRSF1A-associated via death domain;tumor necrosis factor receptor type 1 associated death domain protein;tumor necrosis factor receptor type 1-associated DEATH domain protein;tumor necrosis factor receptor-1-associated protein.
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12; leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses; apoptosis and activation of NF-kappa-B.
Gene Details:
TNFRSF1A associated via death domain
Host:
Rabbit
Immunogen:
Range: Met61 - Leu297
Isotype:
IgG
Molecular Weight:
28 kDa
Protein Details:
Tumor necrosis factor receptor type 1-associated DEATH domain protein
Purification:
Affinity Purified; Protein A Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C|-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody