TLR1 Antibody
Product Sizes
100ul
£322.00
OACD07799-100UL
1ml
£890.00
OACD07799-1ML
About this Product
- SKU:
- OACD07799
- Additional Names:
- CD281;rsc786;TIL;TIL. LPRS5;toll/interleukin-1 receptor-like protein;toll-like receptor 1.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides (PubMed:21078852). Forms the activation cluster TLR2:TLR1:CD14 in response to triacylated lipopeptides; this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid-raft dependent pathway (PubMed:16880211). Acts via MYD88 and TRAF6; leading to NF-kappa-B activation; cytokine secretion and the inflammatory response.
- Gene Details:
- toll like receptor 1
- Host:
- Rabbit
- Immunogen:
- Range: Val114 - Val339
- Isotype:
- IgG
- Molecular Weight:
- 90 kDa
- Protein Details:
- Toll-like receptor 1
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
