SIRPA Antibody
Product Sizes
100ul
£316.00
OACD07304-100UL
1ml
£868.00
OACD07304-1ML
About this Product
- SKU:
- OACD07304
- Additional Names:
- AI835480;Bi;Bit;brain Ig-like molecule with tyrosine-based activation motifs;brain immunological-like with tyrosine-based motifs;CD172;CD172 antigen-like family member A;CD172a;Idd13.2;inhibitory receptor SHPS-1;mSIRP-alpha1;myD-1 antigen;P8;P84;protein tyrosine phosphatase; non-receptor type substrate 1;Pt;Ptpns1;SHP;SHP substrate 1;SHP-1;SHPS-1;signal-regulatory protein alpha-1;SIRP;sirp-alpha-1;tyrosine-protein phosphatase non-receptor type substrate 1.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6; PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons; neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion; growth factors or insulin. Mediates negative regulation of phagocytosis; mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells (By similarity).
- Gene Details:
- signal-regulatory protein alpha
- Host:
- Rabbit
- Immunogen:
- Range: Thr56 - Arg296
- Isotype:
- IgG
- Molecular Weight:
- 32 kDa
- Protein Details:
- Tyrosine-protein phosphatase non-receptor type substrate 1
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
