KITLG Antibody
Product Sizes
100ul
£326.00
OACD07150-100UL
1ml
£912.00
OACD07150-1ML
About this Product
- SKU:
- OACD07150
- Additional Names:
- C-kit ligand;hematopoietic growth factor KL;kit ligand;Kitl;mast cell growth factor;Mgf;SCF;steel factor/kit ligand;Stem cell factor;stem cell factor KL-1.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation; hematopoiesis; stem cell maintenance; gametogenesis; mast cell development; migration and function; and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1; the regulatory subunit of phosphatidylinositol 3-kinase; and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS; RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1; STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1; leading to the production of the cellular signaling molecules diacylglycerol and inositol 1;4;5-trisphosphate. KITLG/SCF acts synergistically with other cytokines; probably interleukins.
- Gene Details:
- KIT ligand
- Host:
- Rabbit
- Immunogen:
- Range: Glu27 - Glu259
- Isotype:
- IgG
- Molecular Weight:
- 28 kDa
- Protein Details:
- Kit ligand
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
